Only ventilation systems that are specially designed and approved for this specific purpose offer reliable protection when physically handling viruses.
For example, these include microbiological safety cabinets approved by TÜV in accordance with EN 12469 (prescribed filter class H 14 in accordance with EN 1822).
Class H 14 HEPA filters retain at least 99.995 % of particles, bacteria and viruses with the size around 100 nm.